Travel to Santorini from Athens either by ferry or by taking a flight.
You can get to Santorini by ferry from Piraeus with frequent departures through the year. These include taking the Blue Star Ferry, which departs Athens at 7:25 every morning (365 days a year) with stops in Paros and Naxos (and sometimes Ios). It takes about 8 hours from Athens to Santorini and the ferry arrives at Santorini at 14:50. The return trip from Santorini to Athens departs at 15:30 and arrives in Athens at 23:15. In the summer months there are evening Blue Star ferries 3 or 4 nights per week from Piraeus to Santorini. They leave Piraeus at around 6pm and arrive in Santorini just after midnight.
Additionally you can go to Santorini by taking the morning highspeed ferry that departs from Piraeus between 7:15 and 7:30 for most days from April 22 to September 25, 2016 which takes about 5 hours from Athens to Santorini. In July and August it will be a Highspeed 6 and only stop in Ios. In April, May, June, and September it will be a Highspeed 4 and also stop in Naxos and Paros (and not run on Sunday).
Finally you can go to Santorini with a catamaran, SeaJet from March 25 to October 31, 2016. This catamaran departs at 7:00am and arrives in Santorini between 11:50 and 12:30 (usually with stops in Mykonos and Naxos). From June 10 to September 11, 2016 there is also an afternoon ferry that departs Piraeus at 14:45 and arrives at Santorini at 20:45.
If you chose to fly from Athens to Santorini you will find noumerous flights per day which go up to 12 during the summer. That is because during the summer period there are additional flights between Santorini and other islands, and charter flights from abroad. The flight’s duration is approximately 45 minutes.
However you chose, there is one thing for sure : Santorini will take your breath away!